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Agromedicine An integration of applied, basic, and clinical sciences focused on health and safety issues involved in modern agriculture including farm families and environments, workers in agricultural associated industries, and consumers of agricultural products. It also involves the social sciences, education and outreach, and community involvement. Biotechnology According to the United States Department of Agriculture, 2001- The use of biological processes of microbes and of plants or animal cells for the benefit of humans. Examples of biotechnology: Genetically modified organisms (GMO’s) RoundupTM tolerant plants: weeds are killed but the desired plants have a gene introduced to make them more resistant to the effects of the pesticide. Confined Animal Feeding Operation Facilities that confine and feed animals for over 45 days in a 12-month period and do not store or grow grain. A concentrated feeding operation contains over 1000 animal units Feedlots Swine confinement facilities Poultry production facilities Density is expressed in animal units (AU) One AU= any of the following One feeder or slaughter cattle 0.7 dairy cow 2.5 swine over 55 pounds Endocrine Disrupter Endocrine disrupter: a compound which mimics or blocks the effect of hormones, e.g. DDT and estrogen Adverse developmental or reproductive abnormalities can occur Endotoxins Toxins released from the cells of dead gram negative bacteria containing a biologically active lipopolysacchride. Farmer’s Hypersensitivity Pneumonitis (FHP) FHP is a form of allergic alveolitis resulting from an immune complex mediated damage with T-lymphocyte mediated reactions and humoral antibody formation leading to an inflammatory process and eventual fibrosis (scarring) of the lungs. There are elements of Type 1 and Type IV allergic reactions. Repeated exposures to high levels of organic dusts containing thermophillic actinomycetes (bacteria) and mold are necessary to cause sensitization. The three forms are: Acute-respiratory distress, cough, febrile reactions, positive blood tests more likely on Farmer’s Lung Panel (antibody tests) Subacute-less inflammatory reaction, more chronic respiratory symptoms, weight loss Chronic-progressive dyspnea on exertion, weight loss, weakness, emphysema Hydroscopic High affinity for water. Hydroscopic compounds will attract and attach to all water molecules and draw them from tissues. Immediately Dangerous to Life and Health (IDLH) Environment that lacks enough oxygen to support life, toxic levels of hydrogen sulfide and methane. Inorganic Dusts Mineral dusts produced by tilling, harvesting, burning fields, harvesting grapes and other fruit. The primary component is silica from diatomaceous earth and granite. The health effects may include interstitial fibrosis or scarring. Organic Dusts These dusts are made up of biologically active ingredients from plant and animal material found in barns, silos, animal confinement operations, and grain storage buildings and elevators. They include microorganisms and their inflammatory byproducts. These dusts are the primary cause of agricultural respiratory disease. Organic Dust Toxic Syndrome An acute inflammatory reaction from breathing in high levels of dusts containing bacteria and endotoxin. This is an inflammatory reaction and not an allergic reaction but is identical to acute FHP in symptoms and signs. Repeated exposure may cause sensitization and lead to FHP in a minority of people. Pesticide Any substance intended for preventing, destroying, repelling, or mitigating any pest Respirators Air purifying respirators-removal of contaminant from breathing air by filtration or chemical absorption Air-supplied respirator-provide clean air from outside source or tank e.g. Air-supplied respirators or self-contained breathing apparatus (SCBA) SLUDGE Muscarinic symptoms-“ all the faucets are turned on” S-salivation L-lacrimation U-urination D-defecation G-gastric distress E-emesis |
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